I am actually quite excited by the possiblity of this. I know Kevin Smith joked about it "must we go tropical?"
There have been worser sequels however. This seems likely to work more than the ill fated Ghostbusters III (which gets more painful the more it drags on).
Good thing is with the makeup Keaton could perhaps still look the same as in 1988.
I would like to see other faces return however. Having watched the cartoon series as a kid I'd hope Burton would bring back the Dietz family. Especially Lydia. Not sure if Winona Ryder or Catherine O' Hara would be back. Although they were recently at the premiere of Frankenweenie together. Think Burton asked them when he had the chance?
Don't think we'll get the Maitlands. Alec Baldwin doesn't look the same now. Plus they were mysteriously absent from the cartoon show. And one we sadly won't get at all is Glenn Sadix as Otho. He passed away last year. Great shame.